Proinflammatory cytokines, sickness behavior, and Alzheimer disease

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Proinflammatory cytokines, sickness behavior, and Alzheimer disease.

BACKGROUND In Alzheimer disease (AD), systemic inflammation is known to give rise to a delirium. However, systemic inflammation also gives rise to other centrally mediated symptoms in the absence of a delirium, a concept known as sickness behavior. Systemic inflammation is characterized by the systemic production of the proinflammatory cytokines tumor necrosis factor-α (TNFα) and interleukin-6 ...

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Proinflammatory cytokines and sickness behavior: implications for depression and cancer-related symptoms.

PURPOSE/OBJECTIVES To review the relationship between proinflammatory cytokine release and resultant sickness behavior; to explore the implications of sickness behavior related to depression and cancer-related symptoms. DATA SOURCES Published articles and book chapters. DATA SYNTHESIS Proinflammatory cytokines (interleukin-1, interleukin-6, and tumor necrosis factor-alpha) are released as p...

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cytokines in meningococcal disease . Proinflammatory and anti - inflammatory

Interleukin-10 (IL-10), an anti-inflammatory cytokine, was measured in 131 children with meningococcal disease. IL-10 concentrations were significantly higher in children who died and correlated positively with proinflammatory cytokines. Children who die from meningococcal disease have high IL-10 concentrations, which do not suppress proinflanmmatory cytokines. (Arch Dis Child 1996;75:453-454)

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Proinflammatory cytokines and viral respiratory disease in pigs.

Swine influenza virus (SIV), porcine respiratory coronavirus (PRCV) and porcine reproductive and respiratory syndrome virus (PRRSV) are enzootic viruses causing pulmonary infections in pigs. The first part of this review concentrates on known clinical and pathogenetic features of these infections. SIV is a primary respiratory pathogen; PRCV and PRRSV, on the contrary, tend to cause subclinical ...

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Proinflammatory and anti-inflammatory cytokines in meningococcal disease.

Interleukin-10 (IL-10), an anti-inflammatory cytokine, was measured in 131 children with meningococcal disease. IL-10 concentrations were significantly higher in children who died and correlated positively with proinflammatory cytokines. Children who die from meningococcal disease have high IL-10 concentrations, which do not suppress proinflammatory cytokines.

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ژورنال

عنوان ژورنال: Neurology

سال: 2011

ISSN: 0028-3878,1526-632X

DOI: 10.1212/wnl.0b013e318225ae07